Hologic

Hologic

Hologic (Photo credit: Wikipedia)

HOLX : NASDAQ : US$20.66
BUY 
Target: US$26.00

COMPANY DESCRIPTION:
Hologic is a women’s health company that offers medical imaging, diagnostic and therapeutic products to hospitals, imaging clinics, private practices, and labs through a 625-rep direct sales force as well as select independent distributors. The company develops and markets products that address a range of women’s health concerns, including breast cancer,  cervical cancer, menorrhagia, osteoporosis and preterm birth and others.

Investment recommendation


HOLX missed FQ2/13 results on the top line and lowered its FY/13 outlook on the top and the bottom. Despite the miss, we see favorable risk-reward in HOLX shares LT, driven by better-than-expected synergies with respect to the GPRO integration, looming conversion to higher price 3D tomo from 2D, and deleveraging of the balance sheet.
Investment highlights
 2Q results. HOLX beat our EPS estimate by 2 cents but missed on revenue by $16M; and more importantly lowered its outlook for F3Q and FY’13.
Revenue shortfall. The ~$18M revenue shortfall from the midpoint of guidance resulted from ThinPrep restructuring in China ($8M impact);
U.S. ThinPrep utilization softness ($4M); and tight capital spending budgets ($6M) for 2D.
 GPRO update. The GenProbe Dx business grew 6% pro forma, below our expectations, driven by Women’s Health MDx (+10%) partially offset by
2% growth in blood screening.
 Guidance/model. HOLX lowered FY’13 rev. guidance by $85M at the midpoint to $2,530M – $2,550M from $2,610M – $2,640B, and FY’13 Adj.
EPS by $0.04 at the midpoint to $1.54-1.56 from $1.58-1.60. We lower our FY’13 revenue estimate to $2,541M from $2,630M and FY’13E EPS to
$1.54 from $1.58. We lowered FY’14E revs to $2,662M from $2,801M and FY’14E Adj. EPS to $1.65 from $1.77.
Valuation
Our $26 price target assumes a 16.8x multiple on our C2013E EPS of
$1.55.

STAAR Surgical Company Target $6.50

STAA : NASDAQ : US$5.51
HOLD 
Target: US$6.50

COMPANY DESCRIPTION:
Founded in 1982, STAAR Surgical is a fully integrated medical device company competing in the global ophthalmology sector, and plays in two primary segments: phakic intraocular lenses (PIOL) used to treat refractive errors such as myopia and astigmatism, and intraocular lenses (IOL) used to treat cataracts.

Investment recommendation


STAAR Surgical announced preliminary Q1 sales that exceeded our/Street estimates led by strong ICL revenue, which grew 24% Y/Y
and exceeded the $10M level for the first time in company history. Q1 results are a terrific start to the year and mark a reversal of three
consecutive quarters of missing Street estimates. For us to get more constructive on the name, we want to see consistent improvement in the
company’s important Asian ICL markets – namely Korea, Japan and China – to accompany this quarter’s solid results in the US & Europe, which drove the ICL upside in Q1.

While we maintain our HOLD rating and $6.50 price target, we continue to carry a bullish bias to the ICL opportunity globally over the medium to long term.
Investment highlights
 STAA preannounced Q1 revenue of $18M (+16%) vs. our $16.4M estimate and the consensus projection of $16.5M.
 Q1 global ICL sales grew ~24% Y/Y, well above our 8.1% estimate, driven by ICL growth of 57% in Europe and 12% in the U.S.
 IOL sales in Q1 were flat due to the negative impact of the foreign exchange rate in Japan, which saw an impressive 25% growth rate in IOL unit sales. We were projecting Y/Y IOL sales growth of 2%. Notably, STAA said it exited Q1 with $900,000 in backorders for the KS-SP Pre-Loaded Acrylic IOLs in Europe, owing to its partner’s inability to produce enough lenses to meet demand.
 We will update our model when STAA reports full results on May 1.

Pernix Therapeutics

Therapy Session 4

Therapy Session 4 (Photo credit: Colorblind Seb)

PTX : NYSE MKT : US$6.26
BUY 
Target: US$14.00 

COMPANY DESCRIPTION:
Pernix Therapeutics Holdings is a specialty pharmaceutical company that develops and manufactures generic and branded prescription and OTC
products, with particular emphasis on pediatrics. PTX is focused in the areas of allergy, upper respiratory, antibiotics and dermatology. PTX is headquartered in The Woodlands, TX.

Pernix announced that it has completed the acquisition of Somaxon Pharmaceuticals (key branded product Silenor for insomnia). The deal adds a nice low-risk, on-market branded product that PTX will give its sales force to reinvigorate sales (similar to Cedax), with also hopes of OTC potential down the road.

With the deal now closed, we would expect management to turn its attention back to more business development opportunities, which should continue to drive P&L upside. We should get more color here in two weeks (March 18), when PTX reports Q4 earnings.

Reiterate BUY rating and $14 target.
Model update – we forecast $0.11 accretion on our 2013 EPS We have updated our model for the closing of the Somaxon deal – we estimate ~$0.11 of accretion on 2013E EPS (and beyond). PTX gave preliminary guidance of $10-15 million in revenue add and $5-10 million in EBITDA for the first year post closing. We have also increased shares outstanding, which did end up near the high end of possible outcomes (3.665 million) given the lower stock price. Our new EPS estimates from 2013-2016 are now $0.39, $0.69, $1.06 and $1.61. That said, PTX is reporting Q4 EPS on Monday, March 18 (two weeks) where we would expect a fuller update around business trends and a chance to revisit our model and assumptions.
Valuation
Our $14 price target is derived from an equal-weighted ~20.5x P/E and ~7.5x EV/EBITDA multiple applied to our 2014 forecasts. PTX currently
trades at 9.1x P/E on our 2014 forecasts.

Herbalife And Carl Ichan ?

Friday night cocktails at the Carl Icahn Lab

Friday night cocktails at the Carl Icahn Lab (Photo credit: throgers)

HLF : NYSE : US$38.77

Herbalife was in the news yet again Friday after Carl Icahn said in a regulatory filing that he had increased his stake in the company to 14 million shares, or roughly 13% of the company’s outstanding shares.

After weeks of speculation over exactly what the famed corporate raider might be doing, Icahn spoke up and put himself on a collision course with William Ackman, a rival activist investor who called Herbalife a house of cards and said he sees the share price going to zero.

The two men famously tussled on cable television in late January when Icahn called Ackman a “major loser” and warned him of trouble ahead in the form of a major short squeeze. Icahn said he wants to meet with Herbalife’s management “regarding the business and strategic alternatives to enhance shareholder value, such as a recapitalization or a going-private transaction.”

The company said, “We welcome all parties who see the same value in Herbalife that we do.”

Optimer Pharmaceuticals, Inc. BUY Target $ 22

Scanning electron micrograph of Clostridium di...

Scanning electron micrograph of Clostridium difficile bacteria from a stool sample. Obtained from the CDC Public Health Image Library. Image credit: CDC/ Lois S. Wiggs (PHIL #6260), 2004. (Photo credit: Wikipedia)

Optimer Pharmaceuticals, Inc.

OPTR : NASDAQ : US$9.50
BUY Target: US$22.00

COMPANY DESCRIPTION:
Optimer Pharmaceuticals is a global biopharmaceutical company that focuses on developing and commercializing innovative hospital specialty products. Optimer developed and commercialized Dificid (fidaxomicin), an antibiotic for the treatment of Clostridium difficile-associated diarrhea (CDAD). The company has also received marketing authorization for fidaxomicin tablets in Canada, and in the European Union under the trade name Dificlir.

Investment recommendation
Reiterate BUY, $22 target on expectation of steady revenue growth driven by unmet need and Dificid’s superior efficacy in Clostridium difficile-associated diarrhea (CDAD). We feel there is still unmet need given relapse rates associated with other Tx, rising incidence of CDAD, and growing severity of the disease. We think the pharmacoeconomics of Dificid Tx will drive uptake over time, despite premium pricing. Our $22 target is based on a DCF of Dificid/Dificlir sales and royalties.
Investment highlights
 We remain confident in the new Dificid launch initiative’s ability to stimulate Rx growth, but note that IMS data for the first two months of Q4/12 indicate that our estimates were high. Prescriptions grew 20% month-over-month in October, but only 3% in November likely due to the holiday week (per weekly IMS data). With two holiday weeks in December, we don’t expect Rx numbers to rebound enough to hit our previous estimates and have thus revised net revenues from 18.8M to 16.7M. Regardless, we still believe in OPTR’s launch initiatives and continue to expect to see full effects of their efforts in Q1.
 CDAD seasonality to peak in Q1/Q2; may help drive sales along with further NTAP utilization and pharmacoeconomic arguments. We continue to believe the Rx Assist program will also benefit Dificid sales trends, along with new CMS readmission penalties (particularly as they cover pneumonia).
 Model changes: We increased R&D spend in the back half of 2013 to account for new trial starts, as well as SG&A spend assuming the Cubist partnership ends after Q2/13.

Health Care : Fortune’s Top Picks

Image representing Pfizer as depicted in Crunc...

Image via CrunchBase

Image representing Gilead Sciences as depicted...

Image via CrunchBase

Three of Fortune’s top 10 stock picks for 2013 are health care related companies. But they are not in big names in the sector, such as Johnson & Johnson (NYSEJNJ [ or Pfizer (NYSE: PFE). They were Align Technology (NASDAQ: ALGN), Fresenius Medical Care (NYSE: FMS) and Gilead Sciences (NASDAQ: GILD).

Here is a quick look at how these three picks have performed recently and what analysts expect from them.

Align Technology

This San Jose, California-based maker of dental and orthodontic devices has a market capitalization of near $2.1 billion. The long-term earnings per share (EPS) growth forecast is more than 17 percent and the operating margin is much than the industry average. But the price-to-earnings (P/E) ratio is higher than the industry average as well. And short interest is about 10 percent of the float, though that is the lowest it has been since May.

Eight of the 12 analysts surveyed by Thomson/First Call who follow the stock recommend buying shares, six of them rating it at Strong Buy. The mean price target, or where analysts expect the stock to go, is almost 22 percent higher than the current share price, though still less than the multiyear high reached in September.

Shares dropped more than 25 percent in mid October following disappointing guidance, and have yet to recover. Because of that drop, the stock has underperformed DENTSPLY International (NASDAQ: XRAY) and the broader markets over the past six months.

Fresenius Medical Care

This German kidney dialysis company operates about 2,900 clinics in approximately 40 countries. It has a market cap of more than $21 billion and a dividend yield of less than one percent. The long-term EPS growth forecast is more than 10 percent, though EPS fell short of consensus estimates in two of the past four quarters. The return on equity is more than 15 percent.

Only three of the five analysts surveyed recommend buying shares, but none recommend selling. But their mean price target represents almost seven percent potential upside, though that is less than the 52-week high reached in October.

Shares are trading in the same neighborhood as at the the beginning of the year, despite starting to recover from a steep pullback in October as Hurricane Sandy bore down on the East Coast. The stock has underperformed competitors Baxter (NYSE: BAX) and DaVita (NYSE: DVA) over the past six months, but has been in line with the S&P 500.

Gilead Sciences

This biopharmaceutical company is headquartered in Foster City, California and sports a market cap of about $56 billion. The P/E ratio is lower than the industry average and the long-term EPS growth forecast is more than 17 percent. The operating margin is better than the industry average and the return on average is more than 33 percent.

All but four or the 29 analysts surveyed recommend buying shares; 11 of them rate it at Strong Buy. They believe the stock has some room to run as their mean price target is more than 10 percent higher than the current share price. That would be a multiyear high.

Shares have pulled back about three percent from the current multiyear high but are still about 90 percent higher than a year ago. Over the past six months, the stock has outperformed larger competitors GlaxoSmithKline (NYSE: GSK) and Pfizer, as well as the broader markets.

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